Acetyl-L-carnitine, also called ALCAR, is perhaps the most effective form of this amino acid for the brain. Studies show that it may be beneficial for people with neurodegenerative diseases. L-carnitine is an amino acid that occurs naturally in animal products, with its highest levels found in red meat. Small amounts are also contained in white meat, fish, milk, avocado, and asparagus. The body can produce carnitine from lysine and methionine, which are two of the essential amino acids, but this process results in small quantities. Therefore, many people choose to take it additionally as a dietary supplement.
Some research suggests that L-carnitine may be useful for treating depression.
In one review of 12 studies, acetyl-L-carnitine significantly reduced symptoms of depression compared to a placebo.
Interestingly, several of the studies included in this review also found that acetyl-L-carnitine was just as effective as antidepressants but caused fewer side effects.
Acetyl-L-carnitine is used to treat various mental disorders, including Alzheimer's disease, age-related memory loss, late-life depression, cognitive problems related to alcoholism, Lyme disease, and severe liver failure (hepatic encephalopathy).
It is also used for fatigue associated with aging and multiple sclerosis, as well as for amyotrophic lateral sclerosis – a disease associated with muscle loss. Furthermore, acetyl-L-carnitine is used to treat hyperactivity in children with attention deficit hyperactivity disorder (ADHD), as well as to address skin aging.
One of the definitively proven actions of this amino acid is that it improves memory reduced as a result of alcohol consumption. Acetyl-L-carnitine intake appears to improve memory in 30-60-year-olds whose alcohol use has led to long-term thinking problems.
This article is for informational purposes only and is not a substitute for professional medical advice. Food supplements are not medicines and do not replace medical treatment.
More from the blog


