You’re on the Sapphire international store. Shopping from Bulgaria? Switch to the Bulgarian store.
Probiotic + Prebiotic, designed to restore gut and microbiome balance from within. Contributes to a calm stomach, stronger immunity, and a calmer mind. Six live strains and acacia fiber to nourish them. Developed by Dr. Nedelya Shtonova.
2 capsules in the morning on an empty stomach, about 30 minutes before breakfast, with a glass of water. One pack of 60 capsules lasts exactly 30 days. Do not chew or dissolve; the capsule is designed to pass through the acidic environment of the stomach.
We ship within one business day; delivery takes 1–2 business days to an address or courier office. For orders over €60, shipping is on us. You can pay by card online or in cash upon delivery.
For adults and children over 12 years of age experiencing intestinal discomfort, bloating after meals, or regular complaints of gas and stomach pain.
Store in a cool, dry place, preferably in the refrigerator. A day or two in transit with the courier is not a problem: the cultures travel dry in the capsule, and the acacia fiber serves as a protective medium for them.
Most probiotics only deliver bacteria. Microbiome 11 preserves and nourishes them: 7 billion live cultures travel to the gut, and 400 mg of acacia fiber keep them alive until they get there. That is why Microbiome 11 is a synbiotic, not an ordinary probiotic.
The ingredients work synergistically to relieve bloating, gas, and heaviness after meals. Live cultures colonize the intestinal lining and support both digestion and nutrient absorption, helping you return to a feeling of lightness.
A large part of the immune system is located around the gut and is "trained" by the bacteria within it. A healthy microbiome makes the body more resistant to seasonal viral infections, and after antibiotics or stomach upset, it helps the flora recover faster.
The gut is called the "second brain" because over 90% of serotonin—the neurotransmitter for mood and sleep—is produced there. When the gut microbiome is in balance, you feel harmony: the mind is calmer, and sleep and mood improve.
Lunch ended ten minutes ago, and your belt is already feeling tight. This formula is aimed precisely at people with this daily discomfort - bloating, gas, heaviness, and irregular gastrointestinal function.
“Good” probiotic bacteria colonize the intestinal lining and support digestion and nutrient absorption. The result customers describe most often: going out to dinner without calculating how it will affect you.
The microbiome regulates the immune system and works continuously to protect the body from infections. The formula supports this foundation both during the viral season and after taking antibiotics.
When the microbiome is disrupted, following antibiotics, stress, or a period of poor nutrition, immunity weakens. A healthy microbiome helps the immune response to be stronger and reinforces the gut flora for faster recovery.
"Balance for the stomach, peace for the mind." The connection between the brain and the gut is extremely strong. When digestion is unsettled, it is felt throughout the entire day.
Over 90% of serotonin is produced in the gut. When there is an imbalance, we feel chronic fatigue, exhaustion, anxiety, or low mood. By restoring the connection between the mind and body, Microbiome 11 helps promote a calmer mind.
When it comes to probiotics, the species alone is not enough. Each culture also has its own designation. Here are our bacteria by name. Click on a strain to see what it is.
| Ingredient | 1 capsule | Daily dose |
|---|---|---|
| Probiotic blend | 100 mg · 3.5 billion CFU | 200 mg · 7 billion CFU |
| Acacia fiber (prebiotic) | 200 mg | 400 mg |
CFU = colony-forming units: the number of live bacteria capable of multiplying. 2 capsules in the morning on an empty stomach, 30 minutes before breakfast.
The microbiome changes slowly and gradually. That is why we think in months, not days. Here is how the intake is usually structured — sensations are individual.
Two capsules in the morning, with a glass of water, before breakfast. Seven billion live bacteria head to your gut. Some people may experience more gas at first, which is a sign that the fiber is fermenting. If this happens, split the capsules: one in the morning, one in the evening, to make the transition to an orderly microbiome easier.
Tip: place the box next to the water glass on the table, not in the cupboard. This way, taking it in the morning becomes a habit from the very first day.
Microbiome 11 is suitable for daily use, but there are conditions in which the intake of a probiotic should be evaluated by a doctor. Check your case below.
The review is at an ingredient level and is intended to provide you with an accurate starting point. It does not replace the opinion of your treating physician.
No. Here is the honest answer that people rarely get.
The capsules easily withstand the delivery time. The refrigerator is for long-term storage at home and is not a strict requirement for the cultures to survive before the packaging is opened.
The cultures are in a dry form within the capsule, which allows them to withstand transport. The acacia fiber in the same capsule acts as a protective environment around the bacteria, and once they reach the intestines, it becomes their food and supports their multiplication.
If the package has been left sitting, do not worry. Storage outside the refrigerator does not mean the cultures are destroyed; colder temperatures simply extend their lifespan. Therefore, it is more important how you store them after opening.
Heat and humidity shorten the shelf life of live cultures, while cool temperatures preserve them for longer, which is why we store our produce under controlled conditions.
Once you receive the package, place the box in the refrigerator. You can even keep it in the freezer - the bacteria thrive in sub-zero temperatures. In the summer, do not leave the product in the car all day. When traveling, take only the capsules you need for the days you are away and leave the box at home in a cool place.
Here is what studies on probiotic strains and acacia fiber show. Swipe with your finger or mouse — and tap the card for details and the source.
The studies focus on probiotic strains from the species included and on acacia fiber. Dietary supplement. Does not replace a varied diet.
"When I put my name on a product, it is not marketing. It is personal responsibility."
In modern life, filled with stress and poor nutrition, our gut flora is under constant pressure. We created Microbiome 11 with the ambition of offering the best Bulgarian probiotic with a clear composition down to the final designation of every strain.
Take 2 capsules daily in the morning on an empty stomach, about 30 minutes before breakfast, with a glass of water. This ensures the cultures reach the intestines in the best possible condition. If you have a sensitive stomach, you can take them during breakfast. Do not exceed the recommended daily dose.
In cases of more severe imbalance, such as after taking antibiotics, the usual course is at least 3 months. For prevention and maintaining intestinal balance, courses of 3 or 6 months are recommended. The product is also suitable for long-term use.
Probiotics are "good" live bacteria. In this case, 6 selected strains of Bifidobacterium and Lactobacillus. Prebiotics are the "food" for them. Microbiome 11 contains 200 mg of acacia fiber in each capsule (400 mg daily) - a 100% natural, soluble fiber that stimulates the growth of good bacteria. The two together are called a synbiotic.
No. Probiotics are also preventive care for the intestinal ecosystem. Stress, rushed eating, travel, and seasonal viruses can suddenly disrupt the balance. You don't need to have a diagnosis to take care of your digestion.
For adults and children over 12 years of age. For vegans and vegetarians. For people experiencing bloating, gas, heaviness after meals, fatigue, or following antibiotic treatment. For pregnant and breastfeeding women - after consultation with their doctor.
Probiotics of this type have no serious contraindications. The only possible side effects, if any occur at all, are mild digestive disturbances (gas or bloating) at the very beginning of intake, while the body adapts to the new bacteria.
It happens to some people and is no cause for concern. Acacia fiber ferments in the gut, similar to when your diet includes more beans, lentils, or vegetables. It subsides within a few days. If you wish, split the capsule intake between morning and evening so that you are taking a smaller amount of bacteria at once.
And it is precisely then that the intestinal flora is in greatest need of support. Take the capsules about 2 hours apart from the antibiotic and continue even after the course has finished.
For most people, probiotics go well with daily therapy, but the decision rests with your doctor. If you are taking levothyroxine, keep in mind that both are taken in the morning on an empty stomach—ask your endocrinologist how to space them out.
The refrigerator is for long-term storage at home. One or two days of transit with the courier are not a problem — the cultures are in dry form inside the capsule, and the acacia fibers also act as a protective environment around them. If you haven't kept it in the refrigerator until now, the cultures are not destroyed; the colder temperature simply extends their shelf life.
Bifidobacterium infantis LBI-04 · Bifidobacterium longum LBL-01 · Bifidobacterium breve LBB-05 · Bifidobacterium lactis LBA-03 · Lactobacillus plantarum LLP-2L · Lactobacillus rhamnosus LLR-K22. Together — a probiotic blend of 200 mg with 7 billion CFU per daily dose.
Every organism has its own pace. Some of our clients report changes as early as the first week, while for others, it is gradual. We recommend evaluating the results after 60 days of regular use — this is the period during which the balance has time to stabilize.
Microbiome 11 is not a weight loss product. It is designed for digestive comfort and microbiome balance. Many people report that their stomach looks flatter when bloating is reduced.
Yes. Sapphire formulas are designed to complement each other — Microbiome 11 pairs perfectly with Gluco 1, Menoflor 6, and Focus 7, provided the daily dose of each is followed.
In addition to sapphire.bg, you can find Microbiome 11 at Subra, dm, 36.6 Pharmacies, and Nove. You can also order by phone: 02 408 5577, Mon–Fri 9:00–17:00.
60 days of regular intake. This is the period during which the balance has time to be maintained.
Formula with 1 mg melatonin for falling asleep more easily and sound sleep
For control of appetite and glucose levels after meals
Balancing symptoms during menopause
Supports brain health and cognitive function
Tones the body and improves focus without the need for coffee
