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Perimenopause · menopause · postmenopause
Menoflor 6
Support for women before, during, and after menopause. Created by Dr. Nedelya Shtonova, Menoflor 6 helps with the main issues of this transition—hot flashes and night sweats, sleep disturbances, low mood, weak bones, lack of energy, and hormonal imbalance—in a non-hormonal way.
6 areas of support
9 EU-authorized claims
Non-hormonal product
Developed by a doctor
Vegan · gluten-free · soy-free
🇪🇺 GMP · manufacturing
Delivery to an address or courier office
Arrives within 1–2 business days · Get free delivery on orders over 60€
Arrives within 1–2 business days · Get free delivery on orders over 60€
Question before ordering?
Call 02 408 5577 · We are open Mon–Fri 9:00–17:00
Call 02 408 5577 · We are open Mon–Fri 9:00–17:00
Registered in the BFSA register No. T162505831/04.08.2025
Produced in the EU according to GMP standards
Produced in the EU according to GMP standards
How to take
2 capsules daily with water, preferably with food. You can take them together or separately in the morning and evening. If ashwagandha has a calming effect on you, many women prefer to take the second capsule in the evening. The 60-capsule pack lasts for 30 days.
How long does it take to feel it
Initial changes in mood and sleep appear after about 2 weeks. Expect a more noticeable difference in hot flashes and energy between the 4th and 6th week. The reasonable timeframe for lasting results is 8 weeks.
Delivery and Payment
We ship within one business day, and delivery takes 1–2 business days to an address or courier office. For orders over €60, shipping is on us. You can pay online by card or in cash upon delivery.
Who is it suitable for
For women in perimenopause, menopause, and postmenopause, experiencing hot flashes and night sweats, mood swings, sleep difficulties, dryness, or challenges with weight and energy. Not intended for pregnant or breastfeeding women, or children. If you are undergoing therapy—including hormone replacement therapy—please refer to the "Can I take this with my therapy?" section below.
Developed by a doctor
Dr. Nedelya Shtonova's formula
9 EU-authorized claims
Proven by research
Non-hormonal pathway
Soy-free, isoflavone-free, hormone-free
Certified product
Produced according to GMP standards in the EU
Before reading about the ingredients
Do you recognize yourselves?
Three fifteen at night. You wake up drenched, open the window, and wait for it to pass. After twenty minutes, you get cold, lie back down, but the sleep is already gone. In the morning, someone says something quite ordinary to you, and you react sharply. This is no exaggeration. This period has a physiology, not a character. Mark what is familiar to you, and we will show you which ingredients work exactly there.
Mark at least one
Whatever you check off, you are not alone in it
Each of those listed is among the most common complaints that women describe during this period. Mark yours and you will see which part of the formula is designed for them.
Where am I right now
Menopause has three stages, but we work for every one of them.
usually 40–50 g
Perimenopause — the period before actual menopause
The cycle is still there, but it is no longer the same: it comes earlier or later, and is heavier or lighter. Estrogen does not drop steadily, but fluctuates, which explains why you feel fine one month, and the next your hormones take over. This is often when the first hot flashes, interrupted sleep, and irritability appear, even though test results show that "everything is normal."
What does Menoflor 6 do here: it supports sleep and inner peace through ashwagandha, while maca is intended for thermoregulation. Many women start exactly at this stage, including at age 42–45.
an average of about 51 years
Menopause — 12 months without a period
Menopause is a single day, looking back: the day after which 12 months have passed without a period. Around this time, symptoms are usually most pronounced. Hot flashes, night sweats, insomnia, mood swings, dryness. From that moment on, bones begin to lose mineral density more quickly because estrogen no longer protects them as it once did.
What does Menoflor 6 do here: it works simultaneously in six areas — hot flashes, sleep, mood, energy, hormonal balance, and bones, where vitamins D3 and K2 make their contribution.
postmenopausal years
Postmenopause — life after the transition
For most women, hot flashes gradually subside, but two things remain: bone and cardiovascular health. Bone mass loss continues quietly, without symptoms, and that is precisely why this stage is about maintenance, not emergency measures.
What does Menoflor 6 do here: vitamin D3 contributes to the normal absorption of calcium and the maintenance of normal bones and muscles, while vitamin K2 contributes to the maintenance of normal bones. Myo-inositol has been studied in postmenopausal women with metabolic changes.
five ingredients at the centre six directions of support
How it works
Five ingredients. Six areas of support.
Menoflor 6 does not target just one symptom. Hot flashes disrupt sleep, lack of sleep ruins your mood, and stress brings back the hot flashes. That is why the formula works on several levels simultaneously.
Hot flashes and night sweats
Thermoregulation is the first thing to be disrupted when estrogen begins to fluctuate. Maca and ashwagandha are the two botanical ingredients in the formula designed specifically for this aspect.
Maca is a Peruvian root from the cabbage and radish family. In a study of early postmenopausal women, maca intake was associated with significantly fewer hot flashes and night sweats on the Kupperman index. What is important is how: in another placebo-controlled study, improvement on the Greene climacteric scale occurred without changing levels of estradiol, FSH, LH, and SHBG, that is, through a non-hormonal pathway.
Sleep and inner tension
KSM-66 Ashwagandha is an adaptogen. A plant that helps the body cope with stress, rather than suppressing a single symptom. It works on the axis that regulates cortisol.
When this axis is chronically activated, cortisol remains high, and high evening cortisol is one of the reasons for fragmented sleep. In placebo-controlled studies, ashwagandha intake has been associated with measurably lower serum cortisol, and a summary of five studies involving 400 people reported better sleep quality, most pronounced in individuals with insomnia. This is why many women prefer the second capsule in the evening.
Bones that lose density
After menopause, bones lose mineral density more rapidly, and this is the part that goes unnoticed until it becomes a problem. This is where the formula has its strongest justification.
Vitamin D3 and vitamin K2 are the ingredients in Menoflor 6 with the strongest health claims permitted in the EU. D3 contributes to the normal absorption of calcium, the maintenance of normal bone condition, and the normal function of muscles and the immune system. K2 contributes to the maintenance of normal bone condition. The two work in tandem: D3 helps calcium to be absorbed, and K2 helps it reach the bones.
The non-hormonal pathway
Menoflor 6 is not a hormone, but stimulates the body naturally.
Many of you either do not want hormone replacement therapy or cannot take it. Therefore, the first question is almost always: "is this hormones?" It is not. Menoflor 6 is a dietary supplement without hormones, without soy, and without the isoflavones usually implied by the word "phytoestrogen." Maca is a cruciferous root, a relative of cabbage, not soy. And the best evidence comes from the studies themselves: in one of them, women reported improvement on the climacteric scale, while the measured levels of estradiol, FSH, LH, and SHBG remained unchanged. The authors conclude that the effect is independent of estrogenic activity.
Menoflor 6 does not replace hormone replacement therapy and is not a medicine. If you are on HRT, it can be taken concurrently, but only under the supervision of your attending physician.
Five ingredients for every part of the transition.
Five ingredients for every part of the transition.
| Ingredient | 1 capsule | Daily dose (2 capsules) |
|---|---|---|
| Myo-inositol (Vitamin B8) | 200 mg | 400 mg |
| Ashwagandha KSM-66 (Withania somnifera) | 100 mg | 200 mg |
| Maca (Lepidium meyenii), yellow | 50 mg | 100 mg |
| Vitamin D3 (cholecalciferol) | 10 µg · 1000 IU | 20 µg · 2000 IU · 400% RDA* |
| Vitamin K2 MK-7 | 50 µg | 100 µg · 133% RDA* |
*RI — reference intake. The ashwagandha is standardized to withanolides.
Nine authorized claims in the EU
Ingredients that don't need advertising
"Vitamin D contributes to the maintenance of normal bones", "...to normal muscle function", "...to the normal function of the immune system". And: "Vitamin K contributes to the maintenance of normal bones".
These are not advertising slogans, but officially authorized health claims under Regulation (EU) No 432/2012. This is the list of claims that are permitted for use on foods in the European Union. Vitamin D has seven such claims, while vitamin K has two. Menoflor 6 contains both, and in amounts far exceeding what is necessary to trigger them.
Food supplement. Not a medicine and not a substitute for a varied diet and a healthy lifestyle.
Here is what to expect and when
Two women of the same age, with the same intake, go through this period in different ways. The sensations are strictly individual. But there is a rhythm that women describe to us often enough for us to share it honestly.
Week 1–2 · The body begins a new rhythm
Two capsules daily with water, preferably with food. Many women prefer the second one in the evening due to the calming effect of ashwagandha. Adaptogens and vitamins begin to build up.
Tip: choose the same time and consume it with something you do every day - your morning coffee, breakfast, or another routine.
What we promise you and what we cannot!
This is our promise to you.
- The entire composition, with exact quantities and the action of the ingredients.
- A formula conceived by a doctor for this specific period.
- Ingredients whose studies we have cited by name.
- An honest answer to the question "can I, given my therapy".
while
🧠 We will not tell you that.
- That the waves will stop from tomorrow. We wouldn't write that.
- That you will sleep like you're twenty every day.
- An exact day on which you are "guaranteed" to feel something.
- That it replaces hormone replacement therapy.
"Can I, given my therapy?"
Several hundred ladies have asked us this question just under Menoflor 6 advertisements. That is why we reviewed the ingredients line by line against the therapies you ask about most often. For most, the answer is a confident "yes," but please read before taking with medications and therapies.
✓
Hormone replacement therapy (HRT)It can be taken together with HRT, but under your doctor’s supervision, as with any supplement added to a therapy. Menoflor 6 does not replace HRT and is not intended to replace it.
✓
Eliquis / Xarelto (newer anticoagulants)Absolutely fine — with the newer anticoagulants, vitamin K does not affect their action. For your peace of mind, mention it to your cardiologist.
✓
Other Sapphire productsCombines with the whole range — the formulas are made to complement each other.
✓
Vitamin D or calcium you already takeYes — just calculate the total amount of vitamin D for the day so you do not double up unnecessarily. The daily dose here is 2000 IU.
✓
Hashimoto’s without medicationYes, but ashwagandha has described cases of affecting thyroid hormones, so here we prefer you to be informed rather than surprised.
✓
Blood pressure or diabetes medicationYes — ashwagandha and myo-inositol support the same markers, so for the first few weeks simply monitor your readings and mention the supplement at your next check-up.
!
Euthyrox / levothyroxineMenoflor 6 has a good safety profile, but it contains ashwagandha, for which there are described cases of increased thyroid hormones. With thyroid therapy, the better option is a short talk with your endocrinologist first. Write to us and we will send you the full composition for the review.
!
Antidepressants and sedativesAshwagandha has a calming effect that may add to your medication. You can take it, but tell your doctor — and if you feel drowsy during the day, move both capsules to the evening.
!
Autoimmune disease or immunosuppressantsAshwagandha may stimulate the immune system. If you take immunosuppressants or have an autoimmune disease, intake should be agreed with your doctor.
!
High blood calcium or sarcoidosisWith high blood calcium or sarcoidosis, vitamin D should only be taken on a doctor’s advice.
!
History of hormone-dependent cancerDiscuss with your oncologist or gynaecologist before taking it — this is a conversation that deserves the full composition in front of them.
✕
Sintrom / warfarin (acenocoumarol)Not suitable: Menoflor 6 contains vitamin K2, which directly counteracts these medicines. If you are concerned about digestion or immunity, Microbiome 11 can be taken with complete peace of mind with Sintrom.
✕
Pregnancy and breastfeedingWe do not recommend taking it during this period. Our answer here is always the same, without exception.
✕
Children and teenagersThe formula is for women going through the transition, not for children.
✕
Liver diseaseDo not take it if you have liver disease — rare but described cases of liver reactions exist for ashwagandha.
We did not find exactly that on the list. Please call 02 408 5577 or write to us — we will check specifically for you and send you the full ingredients list.
The review is ingredient-based and intended to provide an accurate starting point, but it does not replace the opinion of your attending physician. If you would like to discuss it with them, write to us and we will send you the full composition with dosages in a print-friendly format.
The science behind the formula
Here is what researchers have measured regarding ashwagandha, maca, myo-inositol, vitamin D3, and vitamin K2. Swipe with your finger or mouse and click on the card for details and sources.
The studies are on the individual ingredients and the doses used in scientific settings, not on the finished product.
What people who tried it are sharing:
Reviews are personal impressions of customers and do not guarantee the product's effectiveness. Experiences and results are strictly individual.
Why I created Menoflor 6
"The most unfair part of this period is how lonely it feels to go through it. The children have grown up, work continues, everyone around you thinks everything is normal, and you haven't slept in months."
Dr. Nedelya Shtonova
creator of the Sapphire brand
My dears, this period has a physiology, not a character. I wouldn't promise you that everything will stop, because it's not true and because each of you goes through it in your own way. But I also won't let you think that you just have to endure it, because that's the way it is. That is why I created Menoflor 6: five ingredients, listed with their doses, for the six areas in which this period most often shakes us. When I put my name on a product, it is not marketing, but personal responsibility.
Frequently Asked Questions
What is Menoflor 6 and who is it suitable for?
A dietary supplement created by Dr. Nedelya Shtonova for women in perimenopause, menopause, and postmenopause. It contains five active ingredients—myo-inositol, KSM-66 ashwagandha, maca, vitamin D3, and vitamin K2—which work in six areas: hot flashes and thermoregulation, sleep, mood, energy and libido, hormonal balance, and bones. It is also suitable for women who do not want or cannot take hormone replacement therapy, as well as for those who wish to supplement it under medical supervision.
How is Menoflor 6 taken?
2 capsules daily with water, preferably with food. You can take them together or separately - in the morning and evening. Many women prefer the second capsule in the evening due to the calming effect of ashwagandha.
When will I notice an effect?
Initial changes in mood and sleep after about 2 weeks. A more noticeable difference in hot flashes and energy levels between the 4th and 6th week. A reasonable timeframe for drawing conclusions is 8 weeks of consistent use. You may not feel anything during the first two weeks, and that is normal; adaptogens work through accumulation.
What are the main benefits?
Fewer hot flashes and night sweats, more restful sleep, less anxiety and irritability, more energy and vitality, and bone support. Vitamin D3 contributes to the maintenance of normal bones and muscles and the normal function of the immune system, and vitamin K2 to the maintenance of normal bones.
Are there any side effects?
The formula has a good safety profile when the daily dose is followed. The most commonly reported sensation is mild drowsiness due to the adaptogenic effect of ashwagandha; if this occurs, move your intake to the evening. If jaundice, dark urine, or severe itching occurs, stop taking it and contact a doctor. If you are taking medication, see the section "Can I take this with my therapy?" above.
Are these hormones? Does it contain soy?
No. Menoflor 6 contains no hormones, no soy, and none of the isoflavones typically referred to by the term "phytoestrogen." Maca is a cruciferous root, a relative of cabbage, not soy. In a placebo-controlled study, improvement on the climacteric scale occurred while estradiol, FSH, and LH levels remained unchanged.
Can Menoflor 6 replace hormone therapy?
No. Menoflor 6 is a dietary supplement, not a medication, and it does not replace hormone replacement therapy. It is a different approach — non-hormonal — and the decision of whether you need HRT belongs to you and your doctor, not us.
Can I take it along with HRT?
Yes, under the supervision of your attending physician — as with any addition to your therapy. Write to us and we will send you the full composition with dosages in a print-friendly format so that you can take it to your appointment.
Is it suitable for women after surgery or after stopping HRT?
In cases of surgically induced menopause and after stopping HRT, women often experience symptoms more acutely. The formula is suitable for this period as well, but if you are undergoing other therapy or are in post-operative follow-up, intake should be discussed with your attending physician.
Can I take it if I am not yet in menopause?
Yes. Perimenopause begins years before the final period, for some women as early as 40–42, with the first hot flashes, disrupted sleep, and mood swings, even while tests still show "normal" values. Menoflor 6 is designed for this stage as well.
I only have mood swings and poor sleep. Is it suitable?
Yes. You don’t need to have hot flashes to be in perimenopause. For many women, it is sleep and mood that are affected first. Ashwagandha is the part of the formula specifically designed for that.
How long can I take it for?
It is suitable for prolonged daily use; many women remain on it throughout their entire transition. There is no requirement for a break. If you have a liver, autoimmune, or thyroid condition, the duration is determined by your doctor.
Can I combine it with other supplements?
Yes, if the daily doses of the ingredients are not exceeded. If you are already taking vitamin D separately, calculate the total amount; the daily dose here is 2000 IU. It can be combined with all Sapphire products.
How should the product be stored?
In a cool, dry place, at room temperature, away from direct sunlight and out of the reach of small children. Does not require refrigeration.
Is there scientific evidence behind the formula?
Yes. Ashwagandha KSM-66, maca, myo-inositol, vitamin D3, and vitamin K2 are among the most researched ingredients in this field, supported by randomized trials and meta-analyses, including a study on ashwagandha conducted specifically in perimenopausal women. In the "The Science Behind the Formula" section above, we have listed the sources with author, publication, and number.
Where can I buy it in person?
In addition to online, Menoflor 6 is also available at Subra pharmacy chains, dm drugstores, 36.6 Pharmacies, and Nove.
Eight weeks is the period for actual observations.
The 2-pack bundle covers exactly two months and will cost you €0.92 per day.
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